Hydrogen Peroxide Production Activity and Adhesive Properties of Aerococci, Isolated in Women

SE “Dnipropetrovsk medical academy of Health Ministry of Ukraine” Introduction Antagonistic activity of probiotic microorganisms against other species of bacteria is an important mechanism of their ecology and it is widely used in practice. This activity is inherent in many heme-deficient bacteria, which include aerococci, and can be composed of several components: the production of organic acids, antibiotics, lysozyme, hydrogen peroxide and others. [1]. Ability to produce hydrogen peroxide under aerobic conditions and in a state of relative anaerobiosis was established in aerococci. They were divided into strong and weak producers, depending on the amount of peroxides [2]. Lack of data about peroxide-productive ability of aerococci, isolated from the lower genital tract of women, as well as a proven mechanism of hydrogen peroxide excretion in the oxidation of lactic acid [3], led to need in studying the aerococci hydrogen peroxide production level, to create autobacterial drugs, based on aerococci symbiont strains for sanitation of birth canal. Colonization resistance of the vaginal mucous and normal microflora value depends largely on the degree of adhesion of microbial cells to the mucosal surface. Along with numerous studies of lactobacilli adhesive properties to the vaginal epithelium [4, 5, 6], there are no data on the adsorption capacity of aerococci to the vaginal epithelial cells.